In its commitment to excellence the British Hospital constantly incorporates top-level technologies, in this case the new Cryopreservation System with Programmed Descent.
To understand the usefulness of this technology we must understand the objective of cryopreservation, which is to preserve hematopoietic progenitor cells in such a way as to preserve the necessary quantity and with adequate viability, to achieve hematological reconstitution of a patient undergoing treatment. myeloablative. It primarily involves a phase change from a liquid system to a solid, by means of cold, in order to homogeneously and totally block the cellular enzymatic systems, awaiting their subsequent reconstitution and infusion to efficiently repopulate the bone marrow of the patients. patients who are undergoing Hematopoietic Progenitor Cell transplantation, achieving a successful result from a functional point of view.
This equipment allows a programmed, controlled and standardized temperature drop, through a system that has specific software that directs the process and a chamber with connection to liquid Nitrogen, thus ensuring, through the implementation of programmed mechanisms (always the same, with established and objectively demonstrated temperature variation) the decrease in temperature.
It begins with a slow decrease in temperature that achieves a decrease of 1°C/minute that stabilizes the extra and intracellular medium (in which freezing has not yet occurred), thus reaching -10°C, a critical moment where The formation of ice crystals begins and there may be cellular damage. It is at this moment that liquid nitrogen is injected into the chamber in a rapid and sufficient quantity to ensure a temperature drop of 10°C/minute and in this way the formation of crystals is so rapid that it does not allow cellular dehydration to occur. and therefore preserves cell viability, then continuing with different temperature modifications, which lead to the consolidation and stability of the freezing of the product for subsequent storage.
Finally, the software allows you to have a record of said decrease, through a graph so there is quality control of said process.
With this technology the British Hospital is at the same level with the best Hematopoietic Stem Progenitor transplant centers in the world.